Moving downstream

Pathway to artificial pancreas systems revisited: moving downstream.

Artificial pancreas (AP) systems, a long-sought quest to replicate mechanically islet physiology that is lost in diabetes, are reaching the clinic, and the potential of automating insulin delivery is about to be realized. Significant progress has been made, and the safety and feasibility of AP systems have been demonstrated in the clinical research center and more recently in outpatient "real-w...

Multiple downstream proarrhythmic targets for calmodulin kinase II: moving beyond an ion channel-centric focus.

The multifunctional Ca(2+) calmodulin-dependent protein kinase II (CaMKII) has emerged as a pro-arrhythmic signaling molecule. CaMKII can participate in arrhythmia signaling by effects on ion channel proteins, intracellular Ca(2+) uptake and release, regulation of cell death, and by activation of hypertrophic signaling pathways. The pleuripotent nature of CaMKII is reminiscent of another serine...

Tip Leakage Flow Downstream of a Compressor Cascade with Moving End Wall

Moving hands, moving entities.

In this study we investigated with a priming paradigm whether uni and bimanual actions presented as primes differently affected language processing. Animals' (self-moving entities) and plants' (not self-moving entities) names were used as targets. As prime we used grasping hands, presented both as static images and videos. The results showed an interference effect with unimanual action primes (...

Downstream Regulation In